Abstract

BackgroundHIV pre-exposure prophylaxis (PrEP) is a key component of HIV combination prevention strategies and has the potential to decrease the incidence of HIV in men who have sex with men (MSM). This study aimed to evaluate levels of PrEP acceptability and explore factors associated with willingness to use PrEP among MSM in Liuzhou, China.MethodsBetween November 2017 and May 2019, a cross-sectional survey was conducted among 829 MSM. The study participants were recruited through a nonprobability sampling method. The participants’ demographics, HIV/AIDS knowledge, sexual behaviors, drug use and HIV test history were collected. Multivariate logistic regression was performed to identify factors associated with willingness to use PrEP.ResultsA total of 829 MSM completed the survey, and 30.28% (95% CI 27.3–33.4) were willing to use PrEP. In multivariate logistic regression, factors associated with a higher willingness to use PrEP included Zhuang or Han ethnic origin, recruitment through peer introduction or gay venues, pursuit of a higher education level, previous HIV testing and oral sex with a man. Conversely, having casual sex in the past 6 months was associated with a lower willingness to use PrEP.ConclusionsMSM in Liuzhou reported a relatively low level of willingness to use PrEP. The results indicate the need for effective education, targeted intervention, and implementation strategies to promote PrEP acceptance among MSM.

Highlights

  • Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is a key component of HIV combination prevention strategies and has the potential to decrease the incidence of HIV in men who have sex with men (MSM)

  • All participants were tested for HIV screening; 25 were positive and excluded from the study

  • Among eligible MSM, 251 (30.28%, 95% Confidence intervals (CI) 27.3–33.4) reported that they were willing to use PrEP for HIV prevention

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Summary

Introduction

HIV pre-exposure prophylaxis (PrEP) is a key component of HIV combination prevention strategies and has the potential to decrease the incidence of HIV in men who have sex with men (MSM). The government provides a variety of HIV prevention methods, such as condoms, HIV and sexually transmitted infection (STI) testing and antiretroviral therapy (ART), the HIV epidemic among MSM remains uncontrolled, especially in the western part of the country [4, 5]. In view of these trends, there is an urgent need for China to implement new and effective HIV prevention measures among MSM. In China, the government carried out pilot work on HIV PrEP in seven provinces in 2019 and planned to develop national implementation guidelines [11, 12]

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