Abstract

What is already known on this topic?Preclinical trials showed the effectiveness of domestic inactivated vaccine candidates for coronavirus disease 2019 (COVID-19). However, it is necessary to evaluate the willingness of the public to receive future domestic vaccines and to understand factors associated with willingness at the early stages of vaccine development.What is added by this report?Through May 25, 2020, 70.48% were willing to receive future domestic COVID-19 vaccines. Confidence in vaccines had the largest impact on public willingness, while age and presence of underlying chronic disease did not significantly increase public willingness.What are the implications for public health practice?It is necessary to increase awareness of COVID-19 vaccines among people with high risk of severe infection and to build public confidence in vaccines. Releasing accurate, timely, and reliable data to the public can help increase willingness to get vaccinated.

Highlights

  • People who had chronic diseases, who thought COVID-19 infection was not serious, who thought their symptoms would be less severe than others if infected, who thought their life had not been seriously affected during the previous three months, or who thought COVID-19 was likely to rebound in China, were more likely to refuse vaccines

  • This study found that 70% of the general public were willing to be vaccinated with a COVID-19 vaccine, a rate close to the 74% willingness found in a study conducted in France at about the same time as our survey (4)

  • A study in Wuhan city showed that the basic reproduction number (R0) of COVID-19 was 2.24–3.58 (5) in the early phase of the epidemic, indicating that 55.36%–72.07% of the population needs to be immune to the virus to prevent sustained transmission

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Summary

China CDC Weekly

Willingness of the General Public to Receive the COVID-19 Vaccine During a Second-Level Alert — Beijing Municipality, China, May 2020. Preclinical trials showed the effectiveness of domestic inactivated vaccine candidates for coronavirus disease 2019 (COVID-19). It is necessary to increase awareness of COVID-19 vaccines among people with high risk of severe infection and to build public confidence in vaccines. Older age and presence of underlying chronic disease were not shown to significantly increase public willingness. And accurate scientific data are greatly needed to build public confidence in vaccines, especially among people at high risk of severe COVID-19 infection. Preclinical animal studies had shown that inactivated vaccines induced COVID-19-specific neutralizing antibodies in animals and had a protective effect with no observed antibody-dependent enhancement of infection (ADE) (2). The research conducted a survey between May 12, 2020 and May 25, 2020 to determine willingness of the general public to get a future COVID-19 vaccine.

Chinese Center for Disease Control and Prevention
Perception of vaccine effectiveness
Findings
Underlying chronic disease
DISCUSSION
Full Text
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