Abstract
The neurological features of the Williams (WS) and Down (DS) syndromes were compared as part of a large multidisciplinary research center study and reported from the Departments of Neurosciences and Pediatrics, University of California School of Medicine, San Diego, CA.
Highlights
The neurological features of the Williams (WS) and Down (DS) syndromes were compared as part of a large multidisciplinary research center study and reported from the Departments of Neurosciences and Pediatrics, University of California School of Medicine, San Diego, CA
Eight patients with Williams syndrome and six with Down syndrome were matched for age and WISC-R or WAIS scores revealed no significant differences between the two groups (WS: 53.8 ± 7.3; DS: 52.5 ± 8.8)
WS patients were small for gestational age and were more likely to have had early feeding problems and failure to thrive
Summary
The neurological features of the Williams (WS) and Down (DS) syndromes were compared as part of a large multidisciplinary research center study and reported from the Departments of Neurosciences and Pediatrics, University of California School of Medicine, San Diego, CA. Eight patients with Williams syndrome and six with Down syndrome were matched for age (mean ages 16.7 and 15.8 years respectively) and WISC-R or WAIS scores revealed no significant differences between the two groups (WS: 53.8 ± 7.3; DS: 52.5 ± 8.8). DS patients demonstrated nonspecific features of global developmental delay but functioned fairly well for their developmental ages while those with WS demonstrated inpaired orcmotor skills, cerebellar dysfunction, difficulty with drawing, and higher verbal abilities than expected.
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