Abstract

Escolar et al.1 have reported that early transplantation of asymptomatic newborns affected by Krabbe's disease favorably alters the course of the disease. Twenty-five newborns and infants underwent an unrelated cord blood transplantation after a standard myeloablative conditioning regimen with busulphan and cyclophoshamide and the survival was significantly better among asymptomatic newborns than symptomatic infants or untreated controls.

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