Abstract
OBJECTIVE: Existing data indicate that assisted reproductive technologies (ART) may result in alterations in genomic methylation at specific loci, as evidenced by animal models and an increased incidence of imprinting disorders in children conceived via ART. We have previously presented preliminary evidence demonstrating that ART conditions may also result in global alterations of genomic methylation in murine blastocysts. We now present microarray data to further test this hypothesis.
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