Wide-scope target and suspect screening of emerging contaminants in sewage sludge from Nigerian WWTPs by UPLC-qToF-MS

Abstract

There is currently a paucity of scientific data in Africa on the analysis and occurrence of emerging contaminants in sewage sludge. In this work, the occurrence of European Union (EU) Water Framework Directive priority substances and wide-range emerging contaminants were investigated and discussed comprehensively in the sewage sludge samples from three different wastewater treatment plants (WWTPs) in Lagos, Nigeria. The identification strategy was implemented by target and suspect screening in liquid chromatography-high resolution mass spectrometry. 250 compounds were identified in the sewage sludge samples from the investigated WWTPs. From 250 detected compounds, 182 compounds were quantified, and 78 compounds significantly show high environmental risk score (calculated from provisional no-effect concentrations values (PNEC) as well as their environmental quality data (EQs)). Most of contaminants detected at high amount belong to pharmaceuticals and are from hospital WWTP. While the highest concentration (72.4 mg kg−1) was measured for salicylic acid (a non-steroidal anti-inflammatory drug), antibiotics showed high concentrations up to 24.4 and 28.4 mg kg−1 for ciprofloxacin and ofloxacin, respectively. Three simple factors including frequency of exceedance, frequency of occurrence and extent of exceedance were used to aid prioritization of these substances in future monitoring campaigns. This work presents the first comprehensive and wide-scope screening of a large number of emerging contaminants in sewage sludge from Nigerian WWTPs.