Abstract

Presented is a single-ended potentiostat topology with a new interface connection between sensor electrodes and potentiostat circuit to avoid deviation of cell voltage and linearly convert the cell current into voltage signal. Additionally, due to the increased harmonic distortion quantity when detecting low-level sensor current, the performance of potentiostat linearity which causes the detectable current and dynamic range to be limited is relatively decreased. Thus, to alleviate these irregularities, a fully-differential potentiostat is designed with a wide output voltage swing compared to single-ended potentiostat. Two proposed potentiostats were implemented using TSMC 0.18-μm CMOS process for biomedical application. Measurement results show that the fully differential potentiostat performs relatively better in terms of linearity when measuring current from 500 pA to 10 uA. Besides, the dynamic range value can reach a value of 86 dB.

Highlights

  • The field of electrochemical study often involves sensor devices which are used to measure certain quantity of analytes within a given solution

  • One of the common methods of detecting analytes is through the used of amperometric sensor, in which it utilizes a potentiostat hardware, which is used to control the electrode cells for running electroanalytical experiments

  • To alleviate the issues on voltage saturation and linearity, this paper presents a single-ended potentiostat topology with a new interface connection between sensor electrodes and potentiostat

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Summary

Introduction

The field of electrochemical study often involves sensor devices which are used to measure certain quantity of analytes within a given solution. One of the common methods of detecting analytes is through the used of amperometric sensor, in which it utilizes a potentiostat hardware, which is used to control the electrode cells for running electroanalytical experiments. The structure of the potentiostat hardware utilized in amperometric sensor contains three kinds of electrode cells. The potential difference, Vcell, between WE and RE electrodes is measured by a potentiostat and is kept at certain potential value for specific function. This is accomplished by sinking or sourcing currents from or into the sensor through electrode CE, which in turn measures the current. The fundamental operation of each function can be realized through two different circuit configurations: potential control and current control

Potential Control Configuration
Current Measurement Configuration
Single-ended Potentiostat
Fully-differential Potentiostat
Measurement Results and Discussion
Measurement Results for Single-ended Potentiostat
Measurement Results for Fully-differential Potentiostat
Conclusions
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