Abstract

SummaryThe increased use of several different pharmaceutical agents has provided a positive impact to patients benefits. On the other hand, the ophthalmologist is seeing more patients with ocular side effects secondary to such agents. In particular, ocular toxicity induced by cancer chemotherapy, biologic agents and immunesuppressive drugs includes a broad spectrum of disorders, which reflect the peculiar physiological, anatomical and biochemical characteristics of the eye. The progresses achieved by the science in understanding ocular biostructure has allowed a better knowledge on ocular side effects. This achievement assists the ophthalmologist and other specialists to recognize them early and intervene before severe visual impairment occurs. A prompt intervention for the treatment‐related toxicities may also provide the opportunity for a minimization or resolution of an expected side effect. Therefore, ophthalmologist should examine patients for any therapy that can present potential ocular side effects, according to the type of used drug. The biostructure and pathophysiology of potential toxicity of different drugs will be reviewed.

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