Abstract
Objective Testing a new drug, treatment, and medical device clinically is critically important before prescribing it to patient. Not determining the drug’s safety and efficacy through clinical trials might impose life threatening outcomes on its consumers. The research paper describes the critical factors associated for testing any new drugs clinically, as limited research is performed in this field of public health. Study Design A qualitative systematic literature review was performed by mining relevant original peer reviewed research papers as well as some online resources like MedlinePlus due to limited availability of studies on such critical topic. Methods The databases used were Web of Sciences core collection, PubMed, Google scholar. The keywords used to search research papers were “clinical trials”, “testing new drugs”, “history of testing drugs”, “evidence-based medicine”. Conclusion Drugs which are prescribed to critical target population like pregnant women and children should be more often clinically tested if possible as majority of them are available in the market without Food and Drug Administration (FDA) approval. The abusive potential of any new drug could end up taking lives of innocent individuals. More evidence-based medicine can help translate research results on a heterogeneous population efficiently.
Highlights
Today, more emphasis is given to translational research especially in oncology therapeutic area because of its higher failure rates. 1 Clinical trials are one of the ways through which research is translated to provide evidence-based results
Drugs which are prescribed to critical target population like pregnant women and children should be more often clinically tested if possible as majority of them are available in the market without Food and Drug Administration (FDA) approval
“Clinical trials are research studies that test how well new medical approaches work in people
Summary
Looking at the history of new drug development and research, we do not want to sacrifice innocent lives by not testing new drugs pre-clinically. Experiments like the Holocaust of Nazi’s on twins or be it Tuskegee study, have warned us about the psychological, social as well as physical outcomes on the individual. We are not looking for something which can save our lives at the cost of other human beings. Nor we want the consumer to start abusing the drug out of physical or psychological dependence ability of the new drug. The current study takes into consideration Clinical trials in general over specific therapeutic area. Future studies might want to consider other factors regarding optimizing specific therapeutic area clinical trials, the feasibility of the particular sample subjects as well as animal models, and the feasibility of the drug availability at affordable prices
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
