Abstract
Previous work showed that compared to cationic porphyrins under light irradiation, the anionic ones were the strongest tobacco bright yellow cell death inducers. As this result was unexpected in light to literature, it was of importance to try to understand why anionic porphyrins were able to efficiently induce cell detah in tobacco cell suspension. Thus we decided to investigate structure-activity relationships of a serie of anionic porphyrins toward Tobacco Bright Yellow - 2 (TBY-2) cells, namely 5,10,15,20-tetrakis(carboxyphenyl) porphyrin TPPC, its zinc analogue Zn-TPPC, 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrin TPPS, and its zinc analogue Zn-TPPS, 5,10,15,20-tetrakis(4-phosphonatophenyl) porphyrin TPPP. In particular, their charge states as a function of the pH medium, their abilities to generate reactive oxygen species as well as their spectroscopic and photophysical properties have been investigated and correlated to their biological effect.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Photochemistry & Photobiology, A: Chemistry
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
