Abstract

Why and How is the Self-Related to the Brain Midline Regions?

Highlights

  • What the self is and where it comes from has been one of the great problems of philosophy for thousands of years

  • This association between cortical midline structures (CMS) and self is reinforced by the involvement of these regions in other self-oriented processes, such as mind-wandering or stimulus valuation

  • Those midline regions involved in selfprocessing overlap with another network, the default mode network, which shows high brain activity during the so-called resting state, indicating that there may be a special relationship between self-processing and intrinsic activity

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Summary

Introduction

What the self is and where it comes from has been one of the great problems of philosophy for thousands of years. Many such imaging studies have indicated that brain structures along the cortical midline are closely related to self-specific processing. This association between cortical midline structures (CMS) and self is reinforced by the involvement of these regions in other self-oriented processes, such as mind-wandering or stimulus valuation.

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