Abstract

F our children with full trisomy 18 at our hospital had whorled eyebrows (Figure 1). Normally, the eyebrow hairs grow upward at an angle in the medial part, and gradually the angle becomes horizontal in the middle portion and downward at the lateral part, forming a continuous eyebrow arch. In all of our patients, however, the eyebrow at the second-third from the medial side became wide and dense, and the direction of the hair growth was the opposite, upward oblique from the lateral side. The lateral side of the eyebrow was sparse. Where the laterally growing medial hairs and the medially growing lateral hairs met at the two-thirds position of the eyebrow, a whorl was formed. When the lateral part was less sparse and grew in a more upward direction, the whorl was distinct, but

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