Abstract
The emphasis in publications relating to radiotherapy of cancer of the uterine cervix is on standard technics of intracavitary radium combined with parametrial external irradiation. The sharp gradient of dosage rate around the radioactive sources demands, to avoid areas of underdosage, optimal placement of the radioactive sources in relationship to disease. Local failures can be traced to cold spots (9). In this institution's clinical material, (M. D. Anderson Hospital and Tumor Institute, Houston, Texas) a significant percentage of cases are not best handled by standard technics, and many are even totally unsuited for primary intracavitary radium therapy. Megavoltage therapy has opened a new possibility of combining external irradiation and intracavitary radium therapy in the treatment of these patients. Whole pelvis irradiation of 4,000 rads in four weeks prior to intracavitary radium therapy can be used to advantage in selected cases of Stage I and Stage II cancers of the uterine cervix. Doses up to 6,...
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