Abstract
Mycobacterium kansasii is an opportunistic pathogen and one of the most commonly encountered species in individuals with lung disease. We here report the complete genome sequence of 12 clinical isolates of M. kansasii from patients with pulmonary disease in Brazil.
Highlights
Nontuberculous Mycobacterium (NTM) species are widespread in the environment and some species cause opportunistic infections in humans
Mycobacterium kansasii, frequently isolated from tap water, is a slow-growing photochromogenic NTM and a pathogen that is commonly isolated from patients with pre-existing lung disease, similar to other NTM clinical species such as M. abscessus, M. avium complex, M. malmoense and M. xenopi.[1]. In the USA and South America M. kansasii is the second most isolated NTM after M. avium complex[2,3] while in Rio de Janeiro, it is the most frequent NTM to cause pulmonary disease.[4]. Besides chronic bronchopulmonary disease, M. kansasii causes other clinical manifestations such as lymphadenitis[5], skin and soft tissue infection[6], tenosynovitis, arthritis, osteomyelitis and disseminated infection in patients co-infected with human immunodeficiency virus.[7]
Genome features, predicted genes, and GenBank accession numbers of Mycobacterium kansasii strains isolated in Brazil from patients with pulmonary disease
Summary
Nontuberculous Mycobacterium (NTM) species are widespread in the (man-made) environment and some species cause opportunistic infections in humans. Genome features, predicted genes, and GenBank accession numbers of Mycobacterium kansasii strains isolated in Brazil from patients with pulmonary disease
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