Abstract

Over the past decades, drug-resistant Mycobacterium tuberculosis strains have presented a significant challenge, with inadequate diagnosis of tuberculosis (TB) cases. Here, we report the draft whole-genome sequence of drug-resistant M. tuberculosis strain S7, which was isolated from a patient from Tripura, India, who was diagnosed with pulmonary TB.

Highlights

  • The worldwide emergence and spread of tuberculosis (TB) cases resistant to the available anti-TB drugs pose serious public health threats

  • Study protocols adopted in this study were approved by the human ethics committees of the International Centre for Genetic Engineering and Biotechnology (New Delhi, India) and Agartala Government Medical College (Agartala, India)

  • After receiving an informed signed consent form to participate in this study, subjects were recruited at Agartala Government Medical College

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Summary

Introduction

The worldwide emergence and spread of tuberculosis (TB) cases resistant to the available anti-TB drugs pose serious public health threats. Study protocols adopted in this study were approved by the human ethics committees of the International Centre for Genetic Engineering and Biotechnology (New Delhi, India) (protocol ICGEB/IEC/2017/07) and Agartala Government Medical College (Agartala, India) (protocol F.4[6-9]/AGMC/Academic/IEC Committee/2015/8965, dated 25 April 2018). After receiving an informed signed consent form to participate in this study, subjects were recruited at Agartala Government Medical College. The genomic DNA was extracted from the exponentially growing M. tuberculosis S7 culture (optical density at 600 nm, 1.0) following the protocol reported by Warren et al [3].

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