Abstract

(1) Background: Hypertension is a serious medical condition characterized by a persistent increase in blood pressure (BP), which is prevalent in individuals with knee osteoarthritis (KOA). Pharmacological interventions are normally used to treat both hypertension and KOA; however, a more sustainable form of treatment is desirable for these clinical conditions. Whole-body vibration (WBV) exercise has been proposed as a non-pharmacological therapy for reducing both BP and KOA symptomatology. This study aimed to evaluate the antihypertensive effect of WBV in hypertensive individuals with KOA. (2) Methods: Nineteen hypertensive individuals with KOA were randomly allocated to either a control (CG) (n = 9) or a WBV group (WBVG) (n = 10). Subjects in the WBVG were positioned sitting in a chair in front of a vibrating platform (VP) with the feet on the base (peak-to-peak displacement 2.5, 5.0 and 7.5 mm; frequencies 5 to 14 Hz). In the CG, subjects assumed the same position with the VP turned off. The protocols in the CG and WBVG were performed 2 days/week for a total of 5 weeks. (3) Results: No baseline differences (age, anthropometrics, BP parameters and medications) between the groups were found (p > 0.05). WBV exercise reduced systolic BP (SBP: 126.1 ± 2.7 versus 119.1 ± 3.2 mmHg; p = 0.001; post hoc: p = 0.02; F = 23.97) and mean BP (MBP: 82.6 ± 1.8 versus 78.7 ± 1.8, p = 0.001, post hoc: p = 0.02; F = 23.97), while no significant changes were found in diastolic BP (DBP: 68.5 ± 2.2 versus 64.4 ± 2.3; p = 0.11; F = 2.68). (4) Conclusions: WBV might be considered a sustainable therapy for exerting an antihypertensive effect in medicated hypertensive individuals with KOA. This decline in BP might translate to a reduction in pharmacological need, although further studies are necessary to understand the mechanisms underlying the described effect.

Highlights

  • 1.13 billion people worldwide have hypertension [1]. This medical condition is characterized by a persistent increase in blood pressure (BP) [1] that can be associated with several chronic diseases

  • Nineteen individuals with knee osteoarthritis (KOA) were randomly allocated in control group (CG) (n = 9) and WBV group (WBVG) (n = 10)

  • Five individuals from the WBVG returned to perform the second step of the treatment (CG) and four individuals from the CG returned to the WBVG totaling fourteen people in each group (2 males and 12 females) (Figure 1)

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Summary

Introduction

1.13 billion people worldwide have hypertension [1]. This medical condition is characterized by a persistent increase in blood pressure (BP) [1] that can be associated with several chronic diseases (e.g., knee osteoarthritis - KOA [2], metabolic syndrome - MSyn [3,4], obesity [5] and diabetes [3]).KOA, considered a systemic disease, is connected with biomechanical factors and an important inflammatory component affecting articular and periarticular structures [6,7]. 1.13 billion people worldwide have hypertension [1] This medical condition is characterized by a persistent increase in blood pressure (BP) [1] that can be associated with several chronic diseases (e.g., knee osteoarthritis - KOA [2], metabolic syndrome - MSyn [3,4], obesity [5] and diabetes [3]). The new classification for phenotyping KOA involves components of MSyn, such as increased BP associated with cardiovascular risk factors (i.e., “pre-hypertension or hypertension”) [12]. Many studies reported the association between KOA and hypertension [13,14,15]; to our knowledge, only a longitudinal investigation reported the incidence of hypertension in individuals with KOA. The authors of this investigation concluded that individuals with KOA are 13% more likely to develop hypertension than those without KOA [2]

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