Abstract
The paper presents the results of study of the coagulation process of the whole blood with anticoagulant using the method of laser speckle correlation. The clotting time dependence curves of the correlation coefficient have been presented and discussed. Analyzing the changing trend of these curves is possible to assess the clotting time, which prove the capability of using the method of laser speckle correlation for determining the diseases of blood coagulation.
Highlights
As an important adjustable function, the mechanism of blood coagulation plays a key role in protection of biological organs from accidental injuries [1]
The device is in contact with the sample, it is necessary to place a nonmagnetic ball in the sample that is in sample during the entire study and may make to add any changes in the formation of a fibrin clot
To prevent a premature start of the coagulation process, blood was placed in a tube with sodium citrate immediately after collection
Summary
As an important adjustable function, the mechanism of blood coagulation plays a key role in protection of biological organs from accidental injuries [1]. The most effective method for study the mechanisms of blood coagulation is to measure the clotting time of blood. The coagulation factors that complete the coagulation mechanism are present in the plasma [2] In this connection, the method of measuring the clotting time requires the plasma extracted from the blood in clinics. Modern coagulometers do not allow to make a quick assessment of blood clotting time This method is slow and need a large amount of blood for centrifugation to produce plasma. For the analysis carried out using laboratory coagulometers, it is necessary to separate the blood cells from the plasma, place non-magnetic balls.
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