Abstract
BackgroundEating disorders (ED) such as anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED) are often accompanied by a variety of psychological and physical comorbidities. Gastrointestinal (GI) symptoms are a classical feature in most patients with ED. The heterogeneity of studies on this topic is high, making it difficult to have a clear overview. The aim of this systematic review is therefore to provide an overview of subjectively and objectively measured differences and changes in the GI tract in patients with EDs, along with the occurrence of GI complications.MethodsA systematic literature search was conducted in PubMed, Web of Science, and Google Scholar to find all relevant studies examining GI problems in AN, BN, and BED. Quantitative analyses were performed for objective GI physiology measures where applicable.ResultsThe review differentiated between ED types and also between studies that report GI outcomes of ED in (i) human studies with an ED diagnosis excluding case reports that provide an overview of GI problems in ED and (ii) case reports with an ED diagnosis describing rare GI complications in ED. GI symptoms and impaired gastric transit times were frequent features of EDs with specific differences found for the ED types. During the time course of treatment, GI symptoms changed and/or improved but not completely. GI complications extended the range of GI problems observed, including a variety of serious complications such as gastric dilatation.ConclusionsProblems of the GI tract are frequent in patients with ED and it is likely that they complicate therapy, especially in patients with AN.Systematic Review RegistrationPROSPERO registration number: CRD42019100585.
Highlights
Eating disorders (ED) include anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED) and, Other Specified Feeding and Eating Disorders (OSFED) according to the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) criteria [1] as well as the International Classification of Diseases 11 (ICD-11) [2]
GI outcomes which were reported most frequently are presented for all eating disorders together (ED), Anorexia nervosa (AN) and Bulimia nervosa (BN)
The 10 questions listed in the Table 4 legend were applied to each study if considered appropriate, based on OHAT criteria and depending on study design
Summary
Eating disorders (ED) such as anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED) are often accompanied by a variety of psychological and physical comorbidities. Gastrointestinal (GI) symptoms are a classical feature in most patients with ED. The heterogeneity of studies on this topic is high, making it difficult to have a clear overview. The aim of this systematic review is to provide an overview of subjectively and objectively measured differences and changes in the GI tract in patients with EDs, along with the occurrence of GI complications
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.