Abstract

Results: Analysis involving 50 prostate cancer treatment plans and a total of 100 principal OARs suggest relatively strong systematic trends with bladder data but not rectal data. A linearizing transformation applied to the data clarifies interpretation of the results. The residuals provide a measure of the relative quality of the plans with regard to normal tissue sparing. Weightings are used to combine residuals from both OARs according to treatment guidelines and a criterion flagging the need for replanning established. Conclusions: This tool promises to improve the ability to analyze IMRT treatment plans, increase normal tissue sparing and reduce variability. This model can be incorporated into the planning process to report the predicted dose for any OAR for clinicians engaged in IMRT planning. Author Disclosure: K.M. Thompson: None. A.W. Plank: None. S.G. Towns: None. B.H. Bishop: None.

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