Abstract

Six to eight months after total hip arthroplasty, patients only attain 80% of the functional level of control groups. Understanding which functional tasks are most affected could help reduce this deficit by guiding rehabilitation towards them. The timed up-and-go test bundles multiple tasks together in one test and is a good indicator of a patient's overall level of function. Previously, biomechanical analysis of its phases was used to identify specific functional deficits in pathological populations. To the best of our knowledge, this analysis has never been performed in patients who have undergone total hip arthroplasty. Seventy-one total hip arthroplasty patients performed an instrumented timed up-and-go test in a gait laboratory before and six months after surgery; fifty-two controls performed it only once. Biomechanical features were selected to analyse the test's four phases (sit-to-stand, walking, turning, turn-to-sit) and mean differences between groups were evaluated for each phase. On average, six months after surgery, patients' overall test time rose to 80% of the mean of the control group. The walking phase was revealed as the main deficiency before and after surgery (-41 ± 47% and -22 ± 32% slower, respectively). High standard deviations indicated that variability between patients was high. On average, patients showed improved results in every phase of the timed up-and-go test six months after surgery, but residual deficits in function differed between those phases. This simple test could be appropriate for quantifying patient-specific deficits in function and hence guiding and monitoring post-operative rehabilitation in clinical settings.

Highlights

  • Total hip arthroplasty (THA) is a common, cost-effective and usually highly successful surgical procedure to alleviate pain and improve motor function [1] (‘motor function’ will be referred to as ‘function’ throughout this paper to improve readability)

  • All the patients included in this study were diagnosed with primary hip OA, according to the American College of Rheumatology (ACR) criteria [22], and had stage II, III or IV hip OA according to the Kellgren and Lawrence classification

  • The complete results of the principal component analysis (PCA) are presented in S1 Table

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Summary

Introduction

Total hip arthroplasty (THA) is a common, cost-effective and usually highly successful surgical procedure to alleviate pain and improve motor function [1] (‘motor function’ will be referred to as ‘function’ throughout this paper to improve readability). THA improves function for patients with end-stage hip osteoarthritis (OA), patients have not fully recovered function six months and one year after surgery when compared to healthy control groups [2, 3]. Patient function increases from 70% of the level of healthy control groups before surgery to 80% six to eight months afterwards [2]. The most common tools are: (i) patient-reported outcomes (PROMs) [5] (e.g. the Hip disability and Osteoarthritis Outcome Score [6]) that evaluate multiple domains of function through self-administered questionnaires (e.g. personal factors, activities, participation); (ii) clinical evaluations that evaluate body function (e.g. hip range of motion); and, (iii) medical imaging that evaluates body structure (e.g. femoral offset). Clinical tests like the 6-minute walk test, the 30-second chair stand test or the Timed Up-and-Go (TUG) test—often described as performance-based tests [7]—are used to evaluate patients’ capacity as defined by the WHO ICF, i.e. what a person can do in a standardized evaluation setting [4]

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