Whether serum albumin/leukocyte ratio combined with Go-FAR score more accurately predicts the neurological outcome of patients who suffered cardiac arrest

Abstract

Objective: To investigate whether serum albumin/leukocyte ratio combined with good outcome score after resuscitation (GO-FAR score) can improve the prediction of neurological outcomes in patients with cardiac arrest, so that clinical decisions can be made earlier and futile resuscitation can be avoided. Methods:The data of 72 patients with cardiac arrest rescued 2020.01.01-2022.04.30 in the Seventh Affiliated Hospital of Sun Yat-sen University were collected, and the GO-FAR score and albumin/leukocyte ratio of all patients were calculated. The main research outcome was the neurological outcome within one month after cardiac arrest. The brain function performance score (CPC score) was used for assessing neurological outcomes, It was divided into two groups:a good prognosis group (CPC score 1-2) and a poor prognosis group (CPC score 3-5). Multivariate Logistic analysis and ROC curve analysis were performed on the data of the two groups, and conclusions were drawn. Result:Univariate and multivariate analysis found that the albumin/leukocyte ratio and GO-FAR score in the poor prognosis group were lower than those in the good prognosis group, and the difference between the two groups was statistically significant (P < 0.05).The results of ROC curve analysis found that the area under the curve of ALB/WBC, GO-FAR score, and ALB/WBC + GO-FAR score were: 0.782 (95% CI: 0.662 to 0.903), 0.677 (95% CI: 0.493 to 0.862), 0.841 (95% CI: 746-0.936), P < 0.05, and the difference was statistically significant. Malignant tumor, shock rhythm, albumin, and leukocytes were all influencing factors for functional outcomes in patients with cardiac arrest. Conclusion:The combination of GO-FAR score and albumin/leukocyte ratio can better predict neurological outcomes in patients with cardiac arrest, but still cannot make instructions to stop resuscitation. More research is needed to confirm.