Abstract

The recently published “Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study” by van der Valk et al . in Lancet Oncology poses an interesting question (1). Could rectal cancer patients with locally advanced disease treated with neoadjuvant therapy sans resection patients be spared from a major operation, or possibly postponed indefinitely?

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