When Two Isn’t Better Than One: Single Versus Multiple Angiographic Views for Quantitative Flow Ratio

Abstract

Assessing coronary physiology by measuring fractional flow reserve (FFR) to guide percutaneous coronary intervention has been shown in multiple studies to improve clinical outcomes compared with using angiography alone.1,2 Despite the extensive data and clinical guidelines supporting the use of FFR, the adoption of coronary physiology guidance remains low.3 To address potential barriers to uptake, a number of angiography-based coronary physiology tools have been validated that compute FFR from angiographic images.