Abstract

BackgroundThe Chimney graft (CG) procedure is one of the novel modification techniques of the endovascular aneurysm repair (EVAR) surgery to treat suprarenal and juxtarenal abdominal aortic aneurysms. Other indications for the use of CG placement include thoracic and thoracoabdominal aneurysms with supraortic branches orifice involvement and cases of common iliac artery aneurysms with or without internal iliac artery involvement. The technique is used in patients who due to aortic-neck morphology and lack of adequate fixation and/or sealing zones are not eligible for standard EVAR. In this procedure, a parallel stent-graft is placed adjacent to the main body of the aortic endograft to maintain blood supply to renovisceral or supraortic branches, once the body of the aortic stent-graft is deployed. Symptomatic occlusions of the CG with novel renovascular hypertension were not described until now.Case presentationA-64-year-old male patient, presented with new-onset malignant hypertension, 13 months after an EVAR operation with CG placement to the left renal artery. The patient was on preventive clopidrogel therapy, which was withheld temporarily for several days, one month before presentation. Imaging studies revealed a novel form of iatrogenic renovascular hypertension, caused by occlusion of the CG. Any attempt to recanalize the covered stent or revascularize the left kidney was rejected and conservative treatment was chosen. Seven months after presentation, blood pressure was within normal ranges with little need for antihypertensive therapy.ConclusionsPhysicians should be aware that the novel emerging techniques of EVAR to overcome the limitations of the aortic-neck anatomy may still adversely influence the renal outcome with potential development of new-onset hypertension.

Highlights

  • The Chimney graft (CG) procedure is one of the novel modification techniques of the endovascular aneurysm repair (EVAR) surgery to treat suprarenal and juxtarenal abdominal aortic aneurysms

  • Physicians should be aware that the novel emerging techniques of EVAR to overcome the limitations of the aortic-neck anatomy may still adversely influence the renal outcome with potential development of new-onset hypertension

  • Hereby we present a novel etiology of malignant renovascular hypertension caused by a renal artery CG occlusion

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Summary

Conclusions

The newer techniques of EVAR, such as the fenestrated, branched or CG techniques, can pose an increased risk of renal injury because of several mechanisms, including higher doses of nephrotoxic contrast media and instrumentation of the renal arteries, which can lead to emboli and inadequate revascularization. Another report of 28 patients after EVAR with placement of 56 CGs, found one case of renal CG occlusion after 90 days (98.2% GCs patency). One needs to consider the merits versus the risks of withholding antiplatelet therapy in patients after EVAR with CG, even as a temporary measure before invasive procedures. We believe that a reasonable approach before elective operations for patients with EVAR and CG, is to stop antiplatelet therapy, one week prior to elective surgery and to temporarily initiate anticoagulation treatment (e.g. subcutaneous Enoxaparin). A comparison of one-year follow-up of renal outcome in 21 patients treated with EVAR and CG technique versus 21 anatomically-matched patients that underwent an open repair surgery found similar decline of eGFR in both groups.

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14. Hollenberg NK
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