When should children surviving a Wilms tumor be transplanted?

Abstract

Although children with Wilms tumor now have excellent survival rates, some develop end-stage renal disease (ESRD) owing to immediate nephrectomy or later loss of renal function. According to current recommendations, renal transplantation should be delayed for 2 years following Wilms tumor treatment in children, but data from the National Wilms Tumor Study now question such a waiting period.