When managing antipsychotic-induced somnolence, consider using lower-risk agents and promoting good sleep hygiene

Abstract

Somnolence is a common side effect of antipsychotics, although not all agents have the same sedative properties. Antipsychotic-induced somnolence can be managed by selecting a lower-risk agent, initiating treatment at a lower dose with a slower titration and minimizing the use of concurrent somnolence-inducing agents. Good sleep hygiene is also vital. Although data are limited, caffeine, bupropion and stimulants, such as modafinil, armodafinil, amphetamines and methylphenidate, may be useful in treating antipsychotic-induced somnolence.