Abstract

48 patients with exercise-simulated ventricular arrhythmia of high gradation (IV-V degree in classification of Lown, Wolf) were investigated (ECG monitor, Bicycle ergometry, test with nitroglycerin, echocardiography). Observed results proved the contribution of increased symphathetical tone m arrhytmogenesis. Selective long-acting beta-blocker betaxolol was admitted as a pathogenic therapy of such conditions. The control studies demonstrated high antiarrythmic efficacy of betaxolol in the treatment of ischemic ventricular rhytm disturbances in patients with Coronary Artery Disease as well as m hypersymphaticotonia-related non-coronary ventricular arrhythmia.

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