What Will Computational Modeling Approaches Have to Say in the Era of Atomistic Cryo-EM Data?

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVViewpointNEXTWhat Will Computational Modeling Approaches Have to Say in the Era of Atomistic Cryo-EM Data?James S. FraserJames S. FraserDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California 94107, United StatesMore by James S. Fraserhttp://orcid.org/0000-0002-5080-2859, Kresten Lindorff-LarsenKresten Lindorff-LarsenStructural Biology and NMR Laboratory, Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, DK-2200 Copenhagen, DenmarkMore by Kresten Lindorff-Larsenhttp://orcid.org/0000-0002-4750-6039, and Massimiliano Bonomi*Massimiliano BonomiStructural Bioinformatics Unit, Department of Structural Biology and Chemistry; CNRS UMR 3528; C3BI, CNRS USR 3756; Institut Pasteur, 75015 Paris, France*Email: [email protected]More by Massimiliano Bonomihttp://orcid.org/0000-0002-7321-0004Cite this: J. Chem. Inf. Model. 2020, 60, 5, 2410–2412Publication Date (Web):February 24, 2020Publication History Received1 February 2020Published online24 February 2020Published inissue 26 May 2020https://doi.org/10.1021/acs.jcim.0c00123Copyright © 2020 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1358Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (432 KB) Get e-AlertsSUBJECTS:Chemical structure,Computational modeling,Conformational dynamics,Freezing,Theoretical and computational chemistry Get e-Alerts