Abstract
What should the C ('congestive heart failure') represent in the CHA2 DS2 -VASc score?
Highlights
Patients with atrial fibrillation (AF) require anticoagulation therapy when at least two clinical risk factors for stroke or thromboembolism are present, as defined in the CHA2DS2-VASc score.[1]
The criteria for the CHA2DS2-VASc score were, defined and developed at a time when heart failure was more or less restricted to patients who had left ventricular systolic dysfunction [or reduced left ventricular ejection fraction (LVEF)]. Whether these criteria apply to patients who have heart failure with preserved ejection fraction (HFpEF), i.e. whether the C in the CHA2DS2-VASc score ‘counts’ in this population, is unknown.[2]. This is of interest as an increasing proportion of patients with heart failure have HFpEF, AF is more common in HFpEF and these patients have a similar increased risk for stroke or cardiovascular events.[3,4,5]
Data from this study showed that the stroke risk was comparable between the two groups: 4.3% and 4.4% per 100 person-years.[16]
Summary
Bart A.; van Veldhuisen, Dirk J.; Rienstra, Michiel. Document Version Publisher's PDF, known as Version of record. Citation for published version (APA): Mulder, B. What should the C ('congestive heart failure') represent in the CHA(2)DS(2)-VASc score? More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverneamendment. Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
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