Abstract
EVIDENCE-BASED ANSWER The answer is not entirely clear. COX-2 inhibitors appear safer than nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) for patients taking warfarin (SOR: B, cohort and case-control studies). Acetaminophen increases the international normalized ratio (INR) in patients taking warfarin by 0.67 to 0.83 over placebo, but with unclear clinical effect (SOR: C, small RCTs with disease-oriented outcomes).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
