Abstract
The repeated emergence of similar variants of influenza virus is linked to interactions between the virus’s RNA segments.
Highlights
Related research article Jones JE, Le Sage V, Padovani GH, Calderon M, Wright ES, Lakdawala SS. 2021
When an influenza virion infects a host cell, it releases these RNA segments into the cytoplasm, where copies are made by the replication machinery of the host
The phylogenetic trees built by Jones et al supported parallel evolution in human influenza viruses, but the level of parallel evolution varied between the H1N1 and the H3N2 strains, and between variants of the H1N1 strain
Summary
Related research article Jones JE, Le Sage V, Padovani GH, Calderon M, Wright ES, Lakdawala SS. 2021. They studied viral genomic reassortment, which is a major driver of influenza evolution (Figure 1A). The genome of the influenza virus, for example, is divided among eight different RNA segments (namely PB2, PB1, PA, HA, NP, NA, M and NS).
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