What is the utility of routine ANA testing in predicting development of biological DMARD-induced lupus and vasculitis in patients with rheumatoid arthritis? Data from a single-centre cohort

K Takase,A McHugh,M H Buch,S C Horton,S Das,A Ganesha,P Emery,S Savic

doi:10.1136/annrheumdis-2014-205318

What is the utility of routine ANA testing in predicting development of biological DMARD-induced lupus and vasculitis in patients with rheumatoid arthritis? Data from a single-centre cohort

K Takase, A McHugh + Show 6 more

https://doi.org/10.1136/annrheumdis-2014-205318

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Journal: Annals of the Rheumatic Diseases	Publication Date: May 22, 2014
Citations: 43

Affiliation: NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, St James's University Hospital, Leeds Teaching Hospitals NHS Trust

#Tumour Necrosis Factor Inhibitor #Biological Disease Modifying Antirheumatic Drugs + Show 8 more

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Abstract

ObjectiveTo determine whether serial ANA testing predicts biological disease modifying antirheumatic drugs (bDMARD)-associated ANA/dsDNA production in patients with rheumatoid arthritis (RA).MethodsSerial autoantibody profiles, bDMARD treatment sequences and clinical data were...

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