Abstract
Infertility rates increases day by day and major reason can be genetic disorders.Objective: To review the prevalence and effects of genetic defects that can cause infertility.10 to 20% of patients have severe infertility disorders. To find out whether genetic material defects are really major infertility cause or not? And what are their prevalence.. Infertility is common health condition. Genetic cause are majorly unexplained but 2300 genes expressed that can retranslate and their mutation can cause of infertility.Handfull of genes and genetic effects are associated with human genome to express genes. Mostly tests added to check male infertility annually.Methods: I analyse and evaluate 12 articles from (1997-2011) from Google scholar, PubMed etc. All data is reviewed from infertility complaints. The data is extracted from Medline, PubMed and Obsgyne online library.Results: Those studies which conducted between years 1985 to 2011 are included in review. The sample size included more than 300 men and women aged between 20 to 40 years. In this study we evaluated that genomic technologies and advent of fertility tips can help in fertile patients. Metabolic chromosomal defects can be genetic disorders by deletion of chromosomes abnormLly.SOX9 chromosome is also play basic role in men fertility. Semen collection and measurements done and proper advances can be seen through research to follow up infertile patients. Comprehensive diagnosis started to advance the research and to increase the prognostic information.Conclusions: Infertility can be caused by genomic abnormalities and chromosomal abnormalities. Molecular techniques can help to reduce the abnormalities. In reality we are unable to establish genotype phenotype relationship and various testicular pattern to see infertile men.
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