Abstract
Evidence-Based Answer Propranolol, timolol, valproic acid, topiramate, and amitriptyline are FDA-approved and similarly effective for migraine prophylaxis when compared with placebo. Angiotensin-converting enzyme (ACE) inhibitors may be more effective than other treatments such as amitriptyline, anti-epileptics, and NSAIDs. Gabapentin is ineffective for preventing migraines (SOR: A, systematic reviews of RCTs). OnabotulinumtoxinA reduces the frequency of chronic migraine attacks but efficacy compared with other treatments is unknown (SOR: B, one RCT).
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Evidence-based practice : patient-oriented evidence that matters
Paper Title
Journal
Date
