WHAT IS THE LONG-TERM EMOTIONAL AND BEHAVIORAL IMPACT OF GENETIC RISK ASSESSMENT FOR ALZHEIMER'S DISEASE? FINDINGS FROM THE REVEAL STUDY

Abstract

information linked to routine hospital and mortality data, and to be contacted again by the researchers. A second wave of data collection is ongoing (20142017) with additional questions onmemory, carers and diet. The cohort is also being replenished and coverage widened to include the entire Yorkshire and Humber region (pop 5.25mn). The new recruitment target for the cohort is 50,000. In the first wave of recruitment 28,000 adults (1,700 aged 75 or over) returned completed Health Questionnaires. The response rate was 17%. As expected, respondents were more likely to be female, over 55 years, and living in areas of low deprivation. However, the population is broadly representative of the reference population. To date 12 health studies have identified and recruited over 1100 participants to their studies (including randomised controlled trials, qualitative interviews, matched case control studies) and local authorities are using the data to inform their Joint Strategic Needs Assessments. With over 3000 participants likely to receive a diagnosis of dementia in the next five years, the Yorkshire Health Study provides an opportunity to test a range of individual and public health level interventions to treat, manage and/or prevent dementia and to understand more about the health related behaviours that affect the onset and trajectory of dementia.