Abstract
BackgroundWhen endometrial carcinoma invades the cervical stroma, overall survival and disease-free survival decrease. However, it is still controversial whether patients in suspected stage II should be treated with radical hysterectomy. The goal of this study is to describe the role of radical hysterectomy in patients with endometrial carcinoma and cervical involvement.MethodsThis was a retrospective cohort study were a total of 239 patients with endometrial carcinoma with cervical involvement from Mexico City’s National Cancer Institute were divided according to the type of hysterectomy, and the outcomes were compared using statistical analysis.ResultsThe 5-year overall survival was 75.76% for the simple hysterectomy group and 89.19% for the radical hysterectomy group, without achieving statistical significance. The 5-year disease-free survival was 72.95% for the simple hysterectomy group and 64.31% for the radical hysterectomy group, without achieving statistical significance. Radicality was associated with longer surgical times, intraoperative complications, and bleeding over 500 ml.ConclusionsIn patients with endometrial carcinoma with cervical involvement, radical hysterectomy does not improve prognosis or alter adjuvant therapy.
Highlights
When endometrial carcinoma invades the cervical stroma, overall survival and disease-free survival decrease
The goal of this study is to describe the role of radical hysterectomy in patients with endometrial carcinoma and cervical involvement, independent of clinical stage
98 (41%) patients were diagnosed with stage II disease, and 95 (39.7%) were diagnosed with stage III disease
Summary
When endometrial carcinoma invades the cervical stroma, overall survival and disease-free survival decrease It is still controversial whether patients in suspected stage II should be treated with radical hysterectomy. When there is exclusive cervical invasion, defined as International Federation of Gynecology and Obstetrics (FIGO) stage II, the 5-year overall survival decreases to 75%, compared to 88% for stage I [2]. It is still controversial whether patients in suspected stage II should be treated with radical hysterectomy [3, 4]. The goal of this study is to describe the role of radical hysterectomy in patients with endometrial carcinoma and cervical involvement, independent of clinical stage
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