Abstract

Spinal surgery in patients with osteoporosis has an increased risk for instrumentation failure. Many advancements are being developed in biological methods that manipulate cellular differentiation or cellular recruitment to the surgical site using bioactive coating and mechanical changes to the implants such as altering the surface roughness to enhance in-migration of bone through osteoinduction. The goal of this article is to summarize some of the potential advancement expected in the future related to spinal surgery in patients with osteoporosis.

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