Abstract

In 2011 a new Investment Framework was proposed that described how the scale-up of key HIV interventions could dramatically reduce new HIV infections and AIDS-related deaths in low and middle income countries by 2015. This framework included ambitious coverage goals for prevention and treatment services for 2015, resulting in a reduction of new HIV infections by more than half, in line with the goals of the declaration of the UN High Level Meeting in June 2011. However, the approach suggested a leveling in the number of new infections at about 1 million annually—far from the UNAIDS goal of ending AIDS by 2030. In response, UNAIDS has developed the Fast-Track approach that is intended to provide a roadmap to the actions required to achieve this goal. The Fast-Track approach is predicated on a rapid scale-up of focused, effective prevention and treatment services over the next 5 years and then maintaining a high level of programme implementation until 2030. Fast-Track aims to reduce new infections and AIDS-related deaths by 90% from 2010 to 2030 and proposes a set of biomedical, behavioral and enabling intervention targets for 2020 and 2030 to achieve that goal, including the rapid scale-up initiative for antiretroviral treatment known as 90-90-90. Compared to a counterfactual scenario of constant coverage for all services at early-2015 levels, the Fast-Track approach would avert 18 million HIV infections and 11 million deaths from 2016 to 2030 globally. This paper describes the analysis that produced these targets and the estimated resources needed to achieve them in low- and middle-income countries. It indicates that it is possible to achieve these goals with a significant push to achieve rapid scale-up of key interventions between now and 2020. The annual resources required from all sources would rise to US$7.4Bn in low-income countries, US$8.2Bn in lower middle-income countries and US$10.5Bn in upper-middle-income-countries by 2020 before declining approximately 9% by 2030.

Highlights

  • In 2011 a new Investment Framework for HIV/AIDS was proposed to guide efforts towards the rational use of resources to confront the AIDS epidemic [1]

  • The Investment Framework called for all low- and middle-income countries to focus on a set of Basic Programs of proven effectiveness; to implement social as well as program enablers, based on country-specific decisions about their implementation; and context-specific linkage of HIV interventions that support broader development objectives, such as social protection for children, reduction of gender-based violence, and health system strengthening

  • The full implementation of the Investment Framework was expected to avert at least 12.2 million new infections and 7.4 million AIDS-related deaths by 2020, and provide a costeffective means to achieve the goals of the 2011 United Nations General Assembly Political Declaration on HIV/AIDS [2] for 2015, such as reducing sexual transmission by 50%, reducing transmission among those who inject drugs by 50%, and virtual elimination of mother-to-child transmission according to the maximum expected availability of resources by 2015

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Summary

Introduction

In 2011 a new Investment Framework for HIV/AIDS was proposed to guide efforts towards the rational use of resources to confront the AIDS epidemic [1]. The full implementation of the Investment Framework was expected to avert at least 12.2 million new infections and 7.4 million AIDS-related deaths by 2020, and provide a costeffective means to achieve the goals of the 2011 United Nations General Assembly Political Declaration on HIV/AIDS [2] for 2015, such as reducing sexual transmission by 50%, reducing transmission among those who inject drugs by 50%, and virtual elimination of mother-to-child transmission according to the maximum expected availability of resources by 2015. That analysis examined the role of these new prevention technologies in getting to zero new infections. It concluded that new infections could be reduced to as low as 80,000 per year by 2050 with a more ambitious scale-up than the Investment Framework

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