Abstract

Reproductive aging in women is a continuous process that begins prior to birth and extends through the menopausal transition. The theory that menopause is triggered primarily by ovarian aging is supported by the coincident occurrence of follicular depletion, elevated gonadotrophin levels, and subsequent menstrual irregularity with ultimate cessation of bleeding. The aim of this chapter is to present a systematic overview of physiological and endocrinological changes surrounding menopause, as well as to provide the most recent definition of stages of reproductive aging including menopause, menopause transition, and perimenopause.

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