Abstract
The lecture, based on long experience of research, addresses controversial issues in spinal deformity together with some generalizations. The term of scoliosis is defined as a violation of the spine morphogenesis during the early embryonic development, which, in the process of growth, develops into spinal deformity with clinical variants depending on the degree of morphogenesis violation. The etiological factor of scoliosis is ectopic localization of neural crest-derived cells, which are not genetically deterministic to chondrogenesis and the growth process, in the vertebral body growth plates. The local violation of chondrogenesis in the vertebral body growth plates is a cause of the growth asymmetry and spinal deformity development. The variability of structural changes and the progression prediction depend on the degree of violation of morphogenetic processes laid down during embryogenesis. A phenotype of scoliosis is the primary scoliotic or kyphotic deformity of the spine with variants of the disease course depending on its stage. Research Perspective: the creation of an experimental model of scoliosis with clinical variants and the development of preventive correction of the studied pathology.
Highlights
The lecture, based on long experience of research, addresses controversial issues in spinal deformity together with some generalizations
The term of scoliosis is defined as a violation of the spine morphogenesis during the early embryonic development, which, in the process of growth, develops into spinal deformity with clinical variants depending on the degree of morphogenesis violation
The local violation of chondrogenesis in the vertebral body growth plates is a cause of the growth asymmetry and spinal deformity development
Summary
The lecture, based on long experience of research, addresses controversial issues in spinal deformity together with some generalizations. The term of scoliosis is defined as a violation of the spine morphogenesis during the early embryonic development, which, in the process of growth, develops into spinal deformity with clinical variants depending on the degree of morphogenesis violation. A phenotype of scoliosis is the primary scoliotic or kyphotic deformity of the spine with variants of the disease course depending on its stage. Что же такое идиопатический сколиоз?// Хирургия позвоночника.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
