Abstract
Psychiatry, in terms of neuropsychiatry, has experienced an impressive revival in the field of neurology over the past two decades. This especially holds true for epileptology (Reynolds and Trimble, 2009). A large number of studies have addressed depressive and other affective disorders in patients with seizures. Depression is now widely acknowledged as a frequent psychiatric comorbidity of seizure disorders (Barry et al., 2008; LaFrance et al., 2008). Here we critically explore the concept of depression as a comorbidity in epilepsy (see also Hoppe and Elger, 2011). First, we address criteria which differentiate between transiently altered mood states and psychiatric mood disorders. We then show that depression in epilepsy provides a perfect model for the biopsychosocial etiology of depression and discuss related therapeutic approaches. Finally, we provide some general remarks on what is required to maintain or restitute emotional well-being in patients with therapy–refractory epilepsy.
Highlights
Psychiatry, in terms of neuropsychiatry, has experienced an impressive revival in the field of neurology over the past two decades
We critically explore the concept of depression as a comorbidity in epilepsy
We show that depression in epilepsy provides a perfect model for the biopsychosocial etiology of depression and discuss related therapeutic approaches
Summary
Psychiatry, in terms of neuropsychiatry, has experienced an impressive revival in the field of neurology over the past two decades. Mood regulation disorder depressive mood per se is not sufficient for diagnosing a psychiatric disorder (Mula et al, 2008; Holtzheimer and Mayberg, 2011). We suggest defining affective disorders as disorders of mood regulation rather than alterations of mood state (Holtzheimer and Mayberg, 2011; Hoppe and Elger, 2011).
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