Abstract
Late-life depression (LLD) is a serious public health problem with estimated prevalence ranging from 1.8-25 percent in selected groups. LLD is known to negatively impact cognition both acutely and at follow up, even after remission of mood symptoms with antidepressant medications. Up to 50% conversion rate to dementia has been reported during long term follow up of patients with LLD. Electroconvulsive therapy (ECT), the most efficacious treatment for LLD, can be associated with detrimental effects on cognition.
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