Abstract
Gallbladder cancer is a common malignancy of the biliary tract. It is the fifth common malignancy of the gastrointestinal tract in United States [1] and third in Northern India [2]. Despite such high prevalence, there is scanty published literature about this disease in indexed journals. Therefore, this article is intended to provide a brief overview of gallbladder cancer risk factors, based mainly on published evidence from analytical epidemiology and recent research findings of biologists and practising oncologists. Furthermore, an attempt has been made to establish an association between different causative factors and the occurrence of the disease.
Highlights
Anomalous Pancreatic BiliaryAPBDJ allows reflux of pancreatic juice into gallbladder leading to precancerous changes in gallbladder mucosa [52]
Bio-chemistry and Molecular Biology Laboratory, Centre of Advanced Study in Zoology, Banaras Hindu University, Varanasi 221 005, India;
Gallbladder cancer is a common malignancy of the biliary tract
Summary
APBDJ allows reflux of pancreatic juice into gallbladder leading to precancerous changes in gallbladder mucosa [52]. Kimura et al [53] reported APBDJ in 17% patients of gallbladder cancer but in only 3% of other hepatobiliary disorders. Patients with choledochal cysts are more prone to develop gallbladder carcinomas
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
