Abstract

The term of radiosurgery signifies any kind of single application of ionizing radiation energy, in experimental biology or clinical medicine, aiming at the precise and complete destruction of chosen target structures containing healthy and/or pathological cells, without significant concomitant or late radiation damage to adjacent tissues. The goal of this radiosurgical pathology study is to explore the short- and long-term effects of high-dose ionizing radiation on neural tissue and its pathologies with histological, electron-microscopical, tissue culture and biological-biochemical methods. Radiosurgical pathology focuses its scope and microscope for histological, cell, genetic and molecular changes in the human body and experimental animals, or in tissue cultures and other in vitro experiments, generated by the ionizing radiation delivered from radiosurgical devices.

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