What are the Factors Affecting Patient Positioning Accuracy After Image Fusion Guided Target Localization in Stereotactic Body Radiosurgery?

Abstract

Automatic fusion of the localization and simulation images has greatly improved the accuracy and efficiency of image guided radiotherapy (IGRT). Anthropomorphic phantom studies have demonstrated that IGRT systems can achieve 1-mm accuracy at the isocenter point. However, such accuracy could be difficult to realize in actual patients. This study evaluates how factors, such as patient body motion during treatment, image fusion uncertainty due to body deformation, and angular deviation, affect targeting accuracy for patients with spinal radiosurgery.