What 18028 biopsied blastocyst show us: biopsy technique, day of embryo biopsy and blastocyst stage are related to the risk of obtaining an inconclusive chromosomal assessment after trophectoderm biopsy.

Abstract

Background and Aim: PGT-A is a reliable program in the IVF Unit but, occasionally, fails to yield a diagnostic result. The prevalence of inconclusive diagnoses reported in the literature ranges from 0.8 to 6% and, regardless of the etiology, are an inherent limitation of PGT-A that pose a challenge to both patients and clinicians. The objective of our work was to identify causative factors as blastocyst features and laboratory procedures possibly associated with the probability of obtaining an inconclusive result after blastocyst trophectoderm biopsy.