Abstract

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Highlights

  • West Nile virus (WNV) is one of the most widely distributed arboviruses in the world, with endemic foci in Africa, the Middle East, west Asia, North and Central America, parts of Europe and Australia [1]

  • About 20% of persons infected with WNV develop a mild disease, usually referred to as West Nile fever (WNF)

  • The 2008 European Union case definition for WNV infection [28] was used with a slight modification, i.e. the definition of probable cases included clinical and laboratory – but not epidemiological – criteria)

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Summary

Introduction

West Nile virus (WNV) is one of the most widely distributed arboviruses in the world, with endemic foci in Africa, the Middle East, west Asia, North and Central America, parts of Europe and Australia [1]. Two main WNV genetic lineages are known: lineage 1, identified in the majority of the outbreaks in humans and horses in Europe and the United States and lineage 2, which until 2004 had not been detected outside Africa, but since has repeatedly appeared – initially in Hungary in 2004 [7] and 2005–09 [8], in Russia in 2007 [9] and in Austria in 2008–09 [8,10]

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