Abstract
The West-Life project (https://about.west-life.eu/) is a Horizon 2020 project funded by the European Commission to provide data processing and data management services for the international community of structural biologists, and in particular to support integrative experimental approaches within the field of structural biology. It has developed enhancements to existing web services for structure solution and analysis, created new pipelines to link these services into more complex higher-level workflows, and added new data management facilities. Through this work it has striven to make the benefits of European e-Infrastructures more accessible to life-science researchers in general and structural biologists in particular.
Highlights
Recent advances in structure determination techniques have made it possible to investigate large multi-component macromolecular machines rather than single gene products
West-Life, a European Union Horizon 2020 eInfrastructure Virtual Research Environment, is designed to facilitate the use of the associated computational methods. It does this through a set of user-facing services aimed at the international community of structural biologists, and via infrastructure tools aimed at the community of service developers
The West-Life Virtual Research Environment (VRE) provides a complete environment for analysing structural biology data. It consists of multiple components handling data processing, data management, compute resources, infrastructure for authentication and authorisation, quality assurance and user help
Summary
Recent advances in structure determination techniques have made it possible to investigate large multi-component macromolecular machines rather than single gene products. West-Life, a European Union Horizon 2020 eInfrastructure Virtual Research Environment, is designed to facilitate the use of the associated computational methods. It does this through a set of user-facing services aimed at the international community of structural biologists, and via infrastructure tools aimed at the community of service developers. Most services make use of the European Grid Infrastructure (EGI,http://www.egi.eu/) federated highthroughput computing (HTC) resources This enables the computational load to be distributed across over 40 European, Asian and US sites, which support the enmr.eu Virtual Organisation and provide access to over 100,000 CPU cores. West-Life has continued to support and improve the WeNMR services, and has promoted links to MX and cryo-EM services through collaboration with other major European software developers
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