Wells' syndrome after primoinfection by parvovirus B19 in a child

Abstract

To the Editor: The diagnosis of eosinophilic cellulitis—Wells' syndrome (WS)—is based on both recurrent skin lesions and histologic features.1 Clinically, WS presents as a local erythema and edema of the skin resembling bacterial cellulitis with minor systemic symptoms. The histologic picture shows dermal edema, infiltration of eosinophils, and flame figures. Involution and healing occur after several weeks of recurrent skin manifestations.2 Among the numerous associated disorders, parvovirus B19 (PB19) infection has not, to our knowledge, been reported.