Abstract

A neuroelectrode can be easily prepared using a wet-spun fiber of D-sorbitol/PEDOT:PSS. At a D-sorbitol/PEDOT:PSS weight ratio of 6, the fiber is well-modulated with suitable characters, including the morphology, crystallization, diffusion resistance (179 kΩ), and electric double-layer capacitance (2.72 μF), for sensitive recording of brain activity during somatosensory stimulation and seizures. Additionally, the fiber is highly biocompatible with the brain. This study presents a simple and controllable strategy for the chemical construction of conducting polymer-based neurosensors.

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